“Matching with replacement induces two types of correlations that must be accounted for when estimating the variance of estimated treatment effects. The first is a within-matched set correlation in outcomes. Matched subjects within the same matched set have similar values of the propensity score. Subjects who have the same value of the propensity score have measured baseline covariates that come from the same multivariate distribution. In the presence of confounding, baseline covariates are related to the outcome. Thus, matched subjects are more likely to have similar outcomes compared to two randomly selected subjects. The second source of correlation is induced by repeated use of control subjects. Failure to account for this correlation and acting as though the matched control subjects were independent observations will likely result in estimated standard errors that are artificially small and estimated confidence intervals that are artificially narrow. Added complexity is introduced by having subjects cross-classified with matched sets such that the same control subject can belong to more than one matched set.”

*Statistics in Medicine*,

*39*(11), 1623โ1640.]